ABSTRACT
Nephrolithiasis has a high prevalence in population. Our objective was to compare time of stone passage, severity of pain, frequency of the use of analgesics and the course of disability between groups A, B and C. In this randomized controlled trial study, 240 patients were selected .inclusion criteria was all patient with 5-9mm stone diameter, and exclusion criteria was opium addiction. All of patients were categorized in 3 groups with Block Balance Randomize and double blind method. Each group consisted of 80 persons. In group A [i.e. control group] patients were given daily Diclofenac suppositories of 100mg and Diclofenac tablets of 25mg.In group B patients were given Tamsulosin tablets of 0.4 mg in addition to routine treatment and in group C patients were given Terazosin tablets of 2 mg in addition to routine treatment. Patients were visited three months after lithotripsy. The rate of ureteral stone passage in group B [85.5%] was more than group A [80%] and group C [83.3%], the mean expulsion time group A with 14.9 days was more than group B [12.1 days] and group C [12.2 days],also severity of pain on the basis of VAS chart in group B [4.7] less than group A [5.5] and C [5.2], extra analgesic requirement in alpha blockers group [B:4 patients and C:2 patients] less than control group [8 patients], and all of these were non significantly different. alpha blockers are decrease symptoms of pain and no effective response on expulsion of stones